# Data Versioning Release Notes

## August 2024

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies (listed below). I**n August 2024, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible.** If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) for assistance.

Studies to be updated:

| STUDY / CONSENT NAME           | FULL STUDY NAME                                                                  | BDC Version         | Updating to:     |
| ------------------------------ | -------------------------------------------------------------------------------- | ------------------- | ---------------- |
| AFLMU\_HMB-IRB-PUB-COL-NPU-MDS | NHLBI TOPMed - NHGRI CCDG: AF Biobank LMU in the context of the MED Biobank LMU  | phs001543.v2.p1.c1  | phs001543.v3.p1  |
| EOCOPD\_DS-CS-RD               | NHLBI TOPMed - Boston Early-Onset COPD Study                                     | phs000946.v5.p2.c1  | phs000946.v6.p2  |
| CAMP\_DS-AST-COPD              | NHLBI TOPMed - Childhood Asthma Management Program (CAMP)                        | phs001726.v2.p1.c1  | phs001726.v3.p1  |
| SARP\_GRU                      | NHLBI TOPMed - Severe Asthma Research Program (SARP)                             | phs001446.v2.p2.c1  | phs001446.v3.p2  |
| SARP\_DS-AAI-PUB               | NHLBI TOPMed - Severe Asthma Research Program (SARP)                             | phs001446.v2.p2.c2  | phs001446.v3.p2  |
| GENAF\_HMB-NPU                 | NHLBI TOPMed - NHGRI CCDG: The GENetics in Atrial Fibrillation (GENAF) Study     | phs001547.v2.p1.c1  | phs001547.v3.p1  |
| EGCUT\_GRU                     | NHLBI TOPMed - Early-Onset Atrial Fibrillation in the Estonian Biobank           | phs001606.v2.p1.c1  | phs001606.v3.p1  |
| CCAF\_GRU-IRB                  | NHLBI TOPMed: Cleveland Clinic Atrial Fibrillation (CCAF) Study                  | phs001189.v4.p1.c1  | phs001189.v5.p1  |
| BioMe\_HMB-NPU                 | NHLBI TOPMed - NHGRI CCDG: The BioMe Biobank at Mount Sinai                      | phs001644.v2.p2.c1  | phs001644.v3.p2  |
| CHS\_HMB-MDS                   | NHLBI TOPMed: Cardiovascular Health Study                                        | phs001368.v3.p2.c1  | phs001368.v4.p2  |
| CHS\_HMB-NPU-MDS               | NHLBI TOPMed: Cardiovascular Health Study                                        | phs001368.v3.p2.c2  | phs001368.v4.p2  |
| CHS\_DS-CVD-MDS                | NHLBI TOPMed: Cardiovascular Health Study                                        | phs001368.v3.p2.c3  | phs001368.v4.p2  |
| CHS\_DS-CVD-NPU-MDS            | NHLBI TOPMed: Cardiovascular Health Study                                        | phs001368.v3.p2.c4  | phs001368.v4.p2  |

## May 2024

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies (listed below). In May 2024, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible. If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) for assistance.

Studies to be updated:

| STUDY / CONSENT NAME                             | FULL STUDY NAME                                                                                                     | BDC Version        | Updating to:    |
| ------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------- | ------------------ | --------------- |
| BioMe\_HMB-NPU                                   | NHLBI TOPMed - NHGRI CCDG: The BioMe Biobank at Mount Sinai                                                         | phs001644.v1.p1.c1 | phs001387.v2.p2 |
| BioVU\_AF\_HMB-GSO                               | NHLBI TOPMed - NHGRI CCDG: The Vanderbilt University BioVU Atrial Fibrillation Genetics Study                       | phs001624.v1.p1.c1 | phs001624.v2.p2 |
| CAMP\_DS-AST-COPD                                | NHLBI TOPMed: Childhood Asthma Management Program (CAMP)                                                            | phs001726.v1.p1.c1 | phs001726.v2.p1 |
| CARE\_BADGER\_DS-ASTHMA-IRB-COL                  | NHLBI TOPMed: Best ADd-on Therapy Giving Effective Response (BADGER)                                                | phs001728.v1.p1.c2 | phs001728.v2.p1 |
| CARE\_CLIC\_DS-ASTHMA-IRB-COL                    | NHLBI TOPMed: Characterizing the Response to a Leukotriene Receptor Antagonist and an Inhaled Corticosteroid (CLIC) | phs001729.v1.p1.c2 | phs001729.v2.p1 |
| CARE\_PACT\_DS-ASTHMA-IRB-COL                    | NHLBI TOPMed: Pediatric Asthma Controller Trial (PACT)                                                              | phs001730.v1.p1.c2 | phs001730.v2.p1 |
| CARE\_TREXA\_DS-ASTHMA-IRB-COL                   | NHLBI TOPMed: TReating Children to Prevent EXacerbations of Asthma (TREXA)                                          | phs001732.v1.p1.c2 | phs001732.v2.p1 |
| GCPD-A\_DS-ASTHMA-GSO                            | NHLBI TOPMed: Genetic Causes of Complex Pediatric Disorders - Asthma (GCPD-A)                                       | phs001661.v2.p1.c1 | phs001661.v3.p1 |
| GGAF\_GRU                                        | NHLBI TOPMed CCDG: Groningen Genetics of Atrial Fibrillation (GGAF) Study                                           | phs001725.v1.p1.c1 | phs001725.v2.p1 |
| IPF\_DS-ILD-IRB-NPU                              | NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing                                                            | phs001607.v2.p2.c1 | phs001607.v3.p2 |
| IPF\_DS-LD-IRB-NPU                               | NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing                                                            | phs001607.v2.p2.c2 | phs001607.v3.p2 |
| IPF\_DS-PFIB-IRB-NPU                             | NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing                                                            | phs001607.v2.p2.c3 | phs001607.v3.p2 |
| IPF\_DS-PUL-ILD-IRB-NPU                          | NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing                                                            | phs001607.v2.p2.c4 | phs001607.v3.p2 |
| IPF\_HMB-IRB-NPU                                 | NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing                                                            | phs001607.v2.p2.c5 | phs001607.v3.p2 |
| LTRC\_HMB-MDS                                    | NHLBI TOPMed: Lung Tissue Research Consortium (LTRC)                                                                | phs001662.v1.p1.c2 | phs001662.v2.p1 |
| OMG\_SCD\_DS-SCD-IRB-PUB-COL-MDS-RD              | NHLBI TOPMed: Outcome Modifying Genes in Sickle Cell Disease (OMG)                                                  | phs001608.v1.p1.c1 | phs001608.v2.p1 |
| PIMA\_DS-ASTHMA-IRB-COL                          | NHLBI TOPMed: Pathways to Immunologically Mediated Asthma (PIMA)                                                    | phs001727.v1.p1.c2 | phs001727.v2.p1 |
| PUSH\_SCD\_DS-SCD-IRB-PUB-COL                    | NHLBI TOPMed: Pulmonary Hypertension and the Hypoxic Response in SCD (PUSH)                                         | phs001682.v1.p1.c1 | phs001682.v2.p1 |
| Walk\_PHaSST\_SCD\_DS-SCD-IRB-PUB-COL-NPU-MDS-RD | NHLBI TOPMed: Walk-PHaSST Sickle Cell Disease (SCD)                                                                 | phs001514.v1.p1.c2 | phs001514.v2.p1 |
| Walk\_PHaSST\_SCD\_HMB-IRB-PUB-COL-NPU-MDS-GSO   | NHLBI TOPMed: Walk-PHaSST Sickle Cell Disease (SCD)                                                                 | phs001514.v1.p1.c1 | phs001514.v2.p1 |

## April 2024

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies. **In April 2024, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible.** If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) before April 5, 2024 for assistance.

Studies to be updated:

| STUDY / CONSENT NAME                   | FULL STUDY NAME                                                                                                                                        | BDC Version        | Updating to:    |
| -------------------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------ | ------------------ | --------------- |
| AFLMU\_HMB-IRB-PUB-COL-NPU-MDS         | NHLBI TOPMed - NHGRI CCDG: AF Biobank LMU in the context of the MED Biobank LMU                                                                        | phs001543.v1.p1.c1 | phs001543.v2.p1 |
| AustralianFamilialAF\_HMB-NPU-MDS      | NHLBI TOPMed: Australian Familial Atrial Fibrillation Study                                                                                            | phs001435.v1.p1.c1 | phs001435.v2.p1 |
| CCDG\_PMBB\_AF\_HMB-IRB-PUB            | NHLBI TOPMed - NHGRI CCDG: Penn Medicine BioBank Early Onset Atrial Fibrillation Study                                                                 | phs001601.v1.p1.c1 | phs001601.v2.p2 |
| ChildrensHS\_GAP\_GRU                  | NHLBI TOPMed: Children's Health Study (CHS) Integrative Genetic Approaches to Gene-Air Pollution Interactions in Asthma (GAP)                          | phs001602.v1.p1.c1 | phs001602.v2.p1 |
| ChildrensHS\_IGERA\_GRU                | NHLBI TOPMed: Children's Health Study (CHS) Integrative Genomics and Environmental Research of Asthma (IGERA)                                          | phs001603.v1.p1.c1 | phs001603.v2.p1 |
| ChildrensHS\_MetaAir\_GRU              | NHLBI TOPMed: Children's Health Study (CHS) Effects of Air Pollution on the Development of Obesity in Children (Meta-AIR)                              | phs001604.v1.p1.c1 | phs001604.v2.p1 |
| CHIRAH\_DS-ASTHMA-IRB-COL              | NHLBI TOPMed: Chicago Initiative to Raise Asthma Health Equity (CHIRAH)                                                                                | phs001605.v1.p1.c2 | phs001605.v2.p1 |
| DECAF\_GRU                             | NHLBI TOPMed: Determining the association of chromosomal variants with non-PV triggers and ablation-outcome in AF (DECAF)                              | phs001546.v1.p1.c1 | phs001546.v2.p1 |
| EGCUT\_GRU                             | NHLBI TOPMed: Early-onset Atrial Fibrillation in the Estonian Biobank                                                                                  | phs001606.v1.p1.c1 | phs001606.v2.p1 |
| GALA\_DS-LD-IRB-COL                    | NHLBI TOPMed: Genetics of Asthma in Latino Americans (GALA)                                                                                            | phs001542.v1.p1.c2 | phs001542.v2.p1 |
| GENAF\_HMB-NPU                         | NHLBI TOPMed - NHGRI CCDG: The GENetics in Atrial Fibrillation (GENAF) Study                                                                           | phs001547.v1.p1.c1 | phs001547.v2.p1 |
| GeneSTAR\_DS-CVD-IRB-NPU-MDS           | NHLBI TOPMed: Genetic Study of Atherosclerosis Risk (GeneSTAR)                                                                                         | phs001218.v2.p1.c2 | phs001218.v3.p1 |
| GenSalt\_DS-HCR-IRB                    | NHLBI TOPMed: Genetic Epidemiology Network of Salt Sensitivity (GenSalt)                                                                               | phs001217.v2.p1.c1 | phs001217.v3.p1 |
| HCHS-SOL\_HMB                          | NHLBI TOPMed - NHGRI CCDG: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)                                                                 | phs001395.v1.p1.c2 | phs001395.v2.p1 |
| HCHS-SOL\_HMB-NPU                      | NHLBI TOPMed - NHGRI CCDG: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)                                                                 | phs001395.v1.p1.c1 | phs001395.v2.p1 |
| HyperGEN\_GRU-IRB                      | NHLBI TOPMed: HyperGEN - Genetics of Left Ventricular (LV) Hypertrophy                                                                                 | phs001293.v2.p1.c1 | phs001293.v3.p1 |
| INSPIRE\_AF\_DS-MULTIPLE\_DISEASES-MDS | NHLBI TOPMed - NHGRI CCDG: Intermountain INSPIRE Registry                                                                                              | phs001545.v1.p1.c1 | phs001545.v2.p1 |
| JHU\_AF\_HMB-NPU-MDS                   | NHLBI TOPMed - NHGRI CCDG: The Johns Hopkins University School of Medicine Atrial Fibrillation Genetics Study                                          | phs001598.v1.p1.c1 | phs001598.v2.p1 |
| Mayo\_VTE\_GRU                         | NHLBI TOPMed: Whole Genome Sequencing of Venous Thromboembolism (WGS of VTE)                                                                           | phs001402.v2.p1.c1 | phs001402.v3.p1 |
| MGH\_AF\_DS-AF-IRB-RD                  | NHLBI TOPMed - NHGRI CCDG: Massachusetts General Hospital (MGH) Atrial Fibrillation Study                                                              | phs001062.v4.p2.c2 | phs001062.v5.p2 |
| MGH\_AF\_HMB-IRB                       | NHLBI TOPMed - NHGRI CCDG: Massachusetts General Hospital (MGH) Atrial Fibrillation Study                                                              | phs001062.v4.p2.c1 | phs001062.v5.p2 |
| MLOF\_HMB-PUB                          | NHLBI TOPMed: MyLifeOurFuture (MLOF) Research Repository of patients with hemophilia A (factor VIII deficiency) or hemophilia B (factor IX deficiency) | phs001515.v1.p1.c1 | phs001515.v2.p2 |
| MPP\_HMB-NPU-MDS                       | NHLBI TOPMed - NHGRI CCDG: Malmo Preventive Project (MPP)                                                                                              | phs001544.v1.p1.c1 | phs001544.v2.p1 |
| PARTNERS\_HMB                          | NHLBI TOPMed: Partners HealthCare Biobank                                                                                                              | phs001024.v4.p1.c1 | phs001024.v5.p1 |
| pharmHU\_HMB                           | NHLBI TOPMed: Pharmacogenomics of Hydroxyurea in Sickle Cell Disease (PharmHU)                                                                         | phs001466.v1.p1.c1 | phs001466.v2.p1 |
| SAFHS\_DS-DHD-IRB-PUB-MDS-RD           | NHLBI TOPMed: San Antonio Family Heart Study (SAFHS)                                                                                                   | phs001215.v3.p2.c1 | phs001215.v4.p2 |
| SAPPHIRE\_asthma\_DS-ASTHMA-IRB-COL    | NHLBI TOPMed: Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)                                                 | phs001467.v1.p1.c1 | phs001467.v2.p2 |
| Sarcoidosis\_DS-SAR-IRB                | NHLBI TOPMed: African American Sarcoidosis Genetics Resource                                                                                           | phs001207.v2.p1.c1 | phs001207.v3.p1 |
| SAS\_GRU-IRB-PUB-COL-NPU-GSO           | NHLBI TOPMed: Genome-Wide Association Study of Adiposity in Samoans                                                                                    | phs000972.v4.p1.c1 | phs000972.v5.p1 |
| THRV\_DS-CVD-IRB-COL-NPU-RD            | NHLBI TOPMed: Rare Variants for Hypertension in Taiwan Chinese (THRV)                                                                                  | phs001387.v2.p1.c3 | phs001387.v3.p1 |
| WGHS\_HMB                              | NHLBI TOPMed: Novel Risk Factors for the Development of Atrial Fibrillation in Women                                                                   | phs001040.v4.p1.c1 | phs001040.v5.p1 |
| WHI\_HMB-IRB                           | NHLBI TOPMed: Women's Health Initiative (WHI)                                                                                                          | phs001237.v2.p1.c1 | phs001237.v3.p1 |
| WHI\_HMB-IRB-NPU                       | NHLBI TOPMed: Women's Health Initiative (WHI)                                                                                                          | phs001237.v2.p1.c2 | phs001237.v3.p1 |



## July 28th, 2023

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies. **On July 28th 2023, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible.** If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) before July 28th 2023 for assistance.

Studies to be updated:

| STUDY / CONSENT NAME                   | FULL STUDY NAME                                                                                                                  | BDC Version        | Updating to:    |
| -------------------------------------- | -------------------------------------------------------------------------------------------------------------------------------- | ------------------ | --------------- |
| Amish\_HMB-IRB-MDS                     | NHLBI TOPMed: Genetics of Cardiometabolic Health in the Amish                                                                    | phs000956.v4.p1.c2 | phs000956.v5.p1 |
| AustralianFamilialAF\_HMB-NPU-MDS      | NHLBI TOPMed: Australian Familial Atrial Fibrillation Study                                                                      | phs001435.v1.p1.c1 | phs001435.v2.p1 |
| CATHGEN\_DS-CVD-IRB                    | NHLBI TOPMed - NHGRI CCDG: Early-onset Atrial Fibrillation in the CATHeterization GENetics (CATHGEN) Cohort                      | phs001600.v2.p2.c1 | phs001600.v2.p2 |
| ECLIPSE\_DS-COPD-MDS-RD                | NHLBI TOPMed: Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE)                             | phs001472.v1.p1.c1 | phs001472.v2.p1 |
| GENOA\_DS-ASC-RF-NPU                   | NHLBI TOPMed: Genetic Epidemiology Network of Arteriopathy (GENOA)                                                               | phs001345.v2.p1.c1 | phs001345.v3.p1 |
| GenSalt\_DS-HCR-IRB                    | NHLBI TOPMed: Genetic Epidemiology Network of Salt Sensitivity (GenSalt)                                                         | phs001217.v2.p1.c1 | phs001217.v3.p1 |
| GOLDN\_DS-CVD-IRB                      | NHLBI TOPMed: GOLDN Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate                                     | phs001359.v2.p1.c1 | phs001359.v3.p1 |
| miRhythm\_GRU                          | NHLBI TOPMed: Defining the time-dependent genetic and transcriptomic responses to cardiac injury among patients with arrhythmias | phs001434.v1.p1.c1 | phs001434.v2.p1 |
| PARTNERS\_HMB                          | NHLBI TOPMed: Partners HealthCare Biobank                                                                                        | phs001024.v4.p1.c1 | phs001024.v5.p1 |
| pharmHU\_DS-SCD                        | NHLBI TOPMed: Pharmacogenomics of Hydroxyurea in Sickle Cell Disease (PharmHU)                                                   | phs001466.v1.p1.c3 | phs001466.v2.p1 |
| pharmHU\_DS-SCD-RD                     | NHLBI TOPMed: Pharmacogenomics of Hydroxyurea in Sickle Cell Disease (PharmHU)                                                   | phs001466.v1.p1.c2 | phs001466.v2.p1 |
| pharmHU\_HMB                           | NHLBI TOPMed: Pharmacogenomics of Hydroxyurea in Sickle Cell Disease (PharmHU)                                                   | phs001466.v1.p1.c1 | phs001466.v2.p1 |
| REDS-III\_Brazil\_SCD\_GRU-IRB-PUB-NPU | NHLBI TOPMed: REDS-III Brazil Sickle Cell Disease Cohort (REDS-BSCDC)                                                            | phs001468.v2.p1.c1 | phs001468.v3.p1 |
| SAFHS\_DS-DHD-IRB-PUB-MDS-RD           | NHLBI TOPMed: San Antonio Family Heart Study (SAFHS)                                                                             | phs001215.v3.p2.c1 | phs001215.v4.p2 |
| SAPPHIRE\_asthma\_DS-ASTHMA-IRB-COL    | NHLBI TOPMed: Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)                           | phs001467.v1.p1.c1 | phs001467.v2.p2 |
| WGHS\_HMB                              | NHLBI TOPMed: Novel Risk Factors for the Development of Atrial Fibrillation in Women                                             | phs001040.v4.p1.c1 | phs001040.v5.p1 |

## June 30th, 2023

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies. **On June 30th, 2023, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible.** If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) before June 30th, 2023 for assistance.

Studies to be updated:

| Study & Consent           | Study Name                                                                                 | Current Version    | Update To       |
| ------------------------- | ------------------------------------------------------------------------------------------ | ------------------ | --------------- |
| ARIC\_DS-CVD-IRB          | NHLBI TOPMed - NHGRI CCDG: Atherosclerosis Risk in Communities (ARIC)                      | phs001211.v3.p2.c2 | phs001211.v4.p3 |
| ARIC\_HMB-IRB             | NHLBI TOPMed - NHGRI CCDG: Atherosclerosis Risk in Communities (ARIC)                      | phs001211.v3.p2.c1 | phs001211.v4.p3 |
| COPDGene\_DS-CS-RD        | NHLBI TOPMed: Genetic Epidemiology of COPD (COPDGene)                                      | phs000951.v4.p4.c2 | phs000951.v5.p5 |
| COPDGene\_HMB             | NHLBI TOPMed: Genetic Epidemiology of COPD (COPDGene)                                      | phs000951.v4.p4.c1 | phs000951.v5.p5 |
| CRA\_DS-ASTHMA-IRB-MDS-RD | NHLBI TOPMed: The Genetic Epidemiology of Asthma in Costa Rica                             | phs000988.v4.p1.c1 | phs000988.v5.p1 |
| GALAII\_DS-LD-IRB-COL     | NHLBI TOPMed - NHGRI CCDG: Genes-Environments and Admixture in Latino Asthmatics (GALA II) | phs000920.v4.p2.c2 | phs001189.v4.p1 |
| HyperGEN\_DS-CVD-IRB-RD   | NHLBI TOPMed: HyperGEN - Genetics of Left Ventricular (LV) Hypertrophy                     | phs001293.v2.p1.c2 | phs001293.v3.p1 |
| HyperGEN\_GRU-IRB         | NHLBI TOPMed: HyperGEN - Genetics of Left Ventricular (LV) Hypertrophy                     | phs001293.v2.p1.c1 | phs001293.v3.p1 |
| Mayo\_VTE\_GRU            | NHLBI TOPMed: Whole Genome Sequencing of Venous Thromboembolism (WGS of VTE)               | phs001402.v2.p1.c1 | phs001402.v3.p1 |
| MGH\_AF\_DS-AF-IRB-RD     | NHLBI TOPMed - NHGRI CCDG: Massachusetts General Hospital (MGH) Atrial Fibrillation Study  | phs001062.v4.p2.c2 | phs001062.v5.p2 |
| MGH\_AF\_HMB-IRB          | NHLBI TOPMed - NHGRI CCDG: Massachusetts General Hospital (MGH) Atrial Fibrillation Study  | phs001062.v4.p2.c1 | phs001062.v5.p2 |
| Sarcoidosis\_DS-SAR-IRB   | NHLBI TOPMed: African American Sarcoidosis Genetics Resource                               | phs001207.v2.p1.c1 | phs001207.v3.p1 |
| WHI\_HMB-IRB              | NHLBI TOPMed: Women's Health Initiative (WHI)                                              | phs001237.v2.p1.c1 | phs001237.v3.p1 |
| WHI\_HMB-IRB-NPU          | NHLBI TOPMed: Women's Health Initiative (WHI)                                              | phs001237.v2.p1.c2 | phs001237.v3.p1 |

## May 5th, 2023

The Database of Genotypes and Phenotypes (dbGaP) recently released a new version of one or more studies (listed below). **On May 5th, 2023, the BDC ecosystem will begin updating these datasets, and the previous version will no longer be accessible.** If you have approved access to a current version of a dataset listed below, and need to continue using the dataset, contact [biodatacatalyst@nhlbi.nih.gov](mailto:biodatacatalyst@nhlbi.nih.gov) before May 5th, 2023 for assistance.

Studies to be updated:

| STUDY / CONSENT NAME      | FULL NAME                                                                                                              | Current BDC Version | Will be updated to |
| ------------------------- | ---------------------------------------------------------------------------------------------------------------------- | ------------------- | ------------------ |
| CCAF\_AF\_GRU-IRB         | NHLBI TOPMed: Cleveland Clinic Atrial Fibrillation (CCAF) Study                                                        | phs001189.v3.p1.c1  | phs001189.v4.p1    |
| EOCOPD\_DS-CS-RD          | NHLBI TOPMed: Boston Early-Onset COPD Study                                                                            | phs000946.v4.p1.c1  | phs000946.v5.p1    |
| CFS\_DS-HLBS-IRB-NPU      | NHLBI TOPMed: The Cleveland Family Study (CFS)                                                                         | phs000954.v3.p2.c1  | phs000954.v4.p2    |
| JHS\_HMB-IRB-NPU          | NHLBI TOPMed: The Jackson Heart Study (JHS)                                                                            | phs000964.v4.p1.c1  | phs000964.v5.p1    |
| JHS\_DS-FDO-IRB-NPU       | NHLBI TOPMed: The Jackson Heart Study (JHS)                                                                            | phs000964.v4.p1.c2  | phs000964.v5.p1    |
| JHS\_HMB-IRB              | NHLBI TOPMed: The Jackson Heart Study (JHS)                                                                            | phs000964.v4.p1.c3  | phs000964.v5.p1    |
| JHS\_DS-FDO-IRB           | NHLBI TOPMed: The Jackson Heart Study (JHS)                                                                            | phs000964.v4.p1.c4  | phs000964.v5.p1    |
| FHS\_HMB-IRB-MDS          | NHLBI TOPMed: Genomic Activities such as Whole Genome Sequencing and Related Phenotypes in the Framingham Heart Study  | phs000974.v4.p3.c1  | phs000974.v5.p4    |
| FHS\_HMB-IRB-NPU-MDS      | NHLBI TOPMed: Genomic Activities such as Whole Genome Sequencing and Related Phenotypes in the Framingham Heart Study  | phs000974.v4.p3.c2  | phs000974.v5.p4    |
| HVH\_HMB-IRB-MDS          | NHLBI TOPMed: Heart and Vascular Health Study (HVH)                                                                    | phs000993.v4.p2.c1  | phs000993.v5.p2    |
| HVH\_DS-CVD-IRB-MDS       | NHLBI TOPMed: Heart and Vascular Health Study (HVH)                                                                    | phs000993.v4.p2.c2  | phs000993.v5.p2    |
| VAFAR\_HMB-IRB            | NHLBI TOPMed - NHGRI CCDG: The Vanderbilt AF Ablation Registry                                                         | phs000997.v4.p2.c1  | phs000997.v5.p2    |
| VU\_AF\_GRU-IRB           | NHLBI TOPMed: The Vanderbilt Atrial Fibrillation Registry (VU\_AF)                                                     | phs001032.v5.p2.c1  | phs001032.v6.p2    |
| BAGS\_GRU-IRB             | NHLBI TOPMed: The Genetics and Epidemiology of Asthma in Barbados                                                      | phs001143.v3.p1.c1  | phs001143.v4.p1    |
| CHS\_HMB-MDS              | NHLBI TOPMed: Trans-Omics for Precision Medicine (TOPMed) Whole Genome Sequencing Project: Cardiovascular Health Study | phs001368.v2.p2.c1  | phs001368.v3.p2    |
| CHS\_HMB-NPU-MDS          | NHLBI TOPMed: Trans-Omics for Precision Medicine (TOPMed) Whole Genome Sequencing Project: Cardiovascular Health Study | phs001368.v2.p2.c2  | phs001368.v3.p2    |
| CHS\_DS-CVD-NPU-MDS       | NHLBI TOPMed: Trans-Omics for Precision Medicine (TOPMed) Whole Genome Sequencing Project: Cardiovascular Health Study | phs001368.v2.p2.c4  | phs001368.v3.p2    |
| AACAC\_HMB-IRB-COL-NPU    | NHLBI TOPMed: Diabetes Heart Study (DHS) African American Coronary Artery Calcification (AA CAC)                       | phs001412.v2.p1.c1  | phs001412.v3.p1    |
| AACAC\_DS-DHD-IRB-COL-NPU | NHLBI TOPMed: Diabetes Heart Study (DHS) African American Coronary Artery Calcification (AA CAC)                       | phs001412.v2.p1.c2  | phs001412.v3.p1    |

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