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  • Harmonized Data (TOPMed Harmonized Clinical Variables)
  • Table of Studies Included in the TOPMed Harmonized Dataset Available in PIC-SURE

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  1. Written Documentation
  2. Explore Available Data
  3. PIC-SURE User Guide
  4. Getting Started
  5. Available Data and Managing Data Access

TOPMed and TOPMed related datasets

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Last updated 2 years ago

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The BioData Catalyst ecosystem hosts several datasets from the . The PIC-SURE platform has integrated the clinical and genomic data from all studies listed in the Data Access Dashboard. Through the ingestion process, occasionally PIC-SURE will ingest phenotypic data for the TOPMed studies prior to the genomic data.

Harmonized Data (TOPMed Harmonized Clinical Variables)

There are limited amounts of harmonized data available at this time. The TOPMed Data Coordinating Center (DCC) curation team has identified 44 variables that are shared across 17 NHLBI studies and normalized the participant values for these variables.

The 44 harmonized variables available are listed in the table in Appendix 2. For more information on this initiative, you can view the or on the .

Table of Studies Included in the TOPMed Harmonized Dataset Available in PIC-SURE

Atherosclerosis Risk in Communities Study

ARIC

phs000280

Cardiovascular Health Study

CHS

phs000287

Cleveland Family Study

CFS

phs000284

Coronary Artery Risk Development in Young Adults Study

CARDIA

phs000285

Epidemiology of Asthma in Costa Rica Study

CRA

phs000988

Framingham Heart Study

FHS

phs000007

Genetic Epidemiology Network of Arteriopathy

GENOA

phs001238

Genetic Epidemiology of COPD

COPDGene

phs000179

Genetics of Cardiometabolic Health in Amish

AMISH

phs000956

Genome-Wide Association Study of Venous Thrombosis Study

MAYOVTE

phs000289

Heart and Vascular Health Study

HVH

phs001013

Hispanic Community Health Study - Study of Latinos

HCHS-SOL

phs000810

Jackson Heart Study

JHS

phs000286

Multi-Ethnic Study of Atherosclerosis

MESA

phs000209

Study of Adiposity in Samoans

SAS

phs000914

Women’s Health Initiative WHI

WHI

phs000200

NHLBI Trans-Omics for Precision Medicine (TOPMed) program
additional documentation from the TOPMed DCC GitHub repository
NHLBI Trans-Omics for Precision Medicine website