cac_volume_1
Coronary artery calcium volume using CT scan(s) of coronary arteries
decimal
cubic millimeters
UMLS
cac_score_1
Coronary artery calcification (CAC) score using Agatston scoring of CT scan(s) of coronary arteries
decimal
UMLS
cimt_1
Common carotid intima-media thickness, calculated as the mean of two values: mean of multiple thickness estimates from the left far wall and from the right far wall.
decimal
mm
UMLS
cimt_2
Common carotid intima-media thickness, calculated as the mean of four values: maximum of multiple thickness estimates from the left far wall, left near wall, right far wall, and right near wall.
decimal
mm
UMLS
carotid_stenosis_1
Extent of narrowing of the carotid artery.
encoded
UMLS
0=None||1=1%-24%||2=25%-49%||3=50%-74%||4=75%-99%||5=100%
carotid_plaque_1
Presence or absence of carotid plaque.
encoded
UMLS
0=Plaque not present||1=Plaque present
height_baseline_1
Body height at baseline.
decimal
cm
UMLS
current_smoker_baseline_1
Indicates whether subject currently smokes cigarettes.
encoded
UMLS
0=Does not currently smoke cigarettes||1=Currently smokes cigarettes
weight_baseline_1
Body weight at baseline.
decimal
kg
UMLS
ever_smoker_baseline_1
Indicates whether subject ever regularly smoked cigarettes.
encoded
UMLS
0=Never a cigarette smoker||1=Current or former cigarette smoker
bmi_baseline_1
Body mass index calculated at baseline.
decimal
kg/m^2
UMLS
hemoglobin_mcnc_bld_1
Measurement of mass per volume, or mass concentration (mcnc), of hemoglobin in the blood (bld).
decimal
g / dL = grams per deciliter
UMLS
hematocrit_vfr_bld_1
Measurement of hematocrit, the fraction of volume (vfr) of blood (bld) that is composed of red blood cells.
decimal
% = percentage
UMLS
rbc_ncnc_bld_1
Count by volume, or number concentration (ncnc), of red blood cells in the blood (bld).
decimal
millions / microliter
UMLS
wbc_ncnc_bld_1
Count by volume, or number concentration (ncnc), of white blood cells in the blood (bld).
decimal
thousands / microliter
UMLS
basophil_ncnc_bld_1
Count by volume, or number concentration (ncnc), of basophils in the blood (bld).
decimal
thousands / microliter
UMLS
eosinophil_ncnc_bld_1
Count by volume, or number concentration (ncnc), of eosinophils in the blood (bld).
decimal
thousands / microliter
UMLS
neutrophil_ncnc_bld_1
Count by volume, or number concentration (ncnc), of neutrophils in the blood (bld).
decimal
thousands / microliter
UMLS
lymphocyte_ncnc_bld_1
Count by volume, or number concentration (ncnc), of lymphocytes in the blood (bld).
decimal
thousands / microliter
UMLS
monocyte_ncnc_bld_1
Count by volume, or number concentration (ncnc), of monocytes in the blood (bld).
decimal
thousands / microliter
UMLS
platelet_ncnc_bld_1
Count by volume, or number concentration (ncnc), of platelets in the blood (bld).
integer
thousands / microliter
UMLS
mch_entmass_rbc_1
Measurement of the average mass (entmass) of hemoglobin per red blood cell(rbc), known as mean corpuscular hemoglobin (MCH).
decimal
pg = picogram
UMLS
mchc_mcnc_rbc_1
Measurement of the mass concentration (mcnc) of hemoglobin in a given volume of packed red blood cells (rbc), known as mean corpuscular hemoglobin concentration (MCHC).
decimal
g /dL = grams per deciliter
UMLS
mcv_entvol_rbc_1
Measurement of the average volume (entvol) of red blood cells (rbc), known as mean corpuscular volume (MCV).
decimal
fL = femtoliter
UMLS
pmv_entvol_bld_1
Measurement of the mean volume (entvol) of platelets in the blood (bld), known as mean platelet volume (MPV or PMV).
decimal
fL = femtoliter
UMLS
rdw_ratio_rbc_1
Measurement of the ratio of variation in width to the mean width of the red blood cell (rbc) volume distribution curve taken at +/- 1 CV, known as red cell distribution width (RDW).
decimal
% = percentage
UMLS
bp_systolic_1
Resting systolic blood pressure from the upper arm in a clinical setting.
decimal
mmHg
UMLS
bp_diastolic_1
Resting diastolic blood pressure from the upper arm in a clinical setting.
decimal
mmHg
UMLS
antihypertensive_meds_1
Indicator for use of antihypertensive medication at the time of blood pressure measurement.
encoded
UMLS
0=Not taking antihypertensive medication||1=Taking antihypertensive medication
race_1
Harmonized race category of participant.
encoded
UMLS
AI_AN=American Indian_Alaskan Native or Native American||Asian=Asian||Black=Black or African American||HI_PI=Native Hawaiian or other Pacific Islander||Multiple=More than one race||Other=Other race||White=White or Caucasian
ethnicity_1
Indicator of Hispanic or Latino ethnicity.
encoded
UMLS
both=ethnicity component dbGaP variable values for a subject were inconsistent/contradictory (e.g. over multiple visits)||HL=Hispanic or Latino||notHL=not Hispanic or Latino
hispanic_subgroup_1
classification of Hispanic/Latino background for Hispanic/Latino subjects where country or region of origin information is available
encoded
UMLS
CentralAmerican=Central American||CostaRican=from Costa Rica||Cuban=Cuban||Dominican=Dominican||Mexican=Mexican||PuertoRican=Puerto Rican||SouthAmerican=South American
annotated_sex_1
Subject sex, as recorded by the study.
encoded
UMLS
female=Female||male=Male
geographic_site_1
Recruitment/field center, baseline clinic, or geographic region.
encoded
UMLS
subcohort_1
A distinct subgroup within a study, generally indicating subjects who share similar characteristics due to study design. Subjects may belong to only one subcohort.
encoded
UMLS
lipid_lowering_medication_1
Indicates whether participant was taking any lipid-lowering medication at blood draw to measure lipids phenotypes
encoded
UMLS
0=Participant was not taking lipid-lowering medication||1=Participant was taking lipid-lowering medication.
fasting_lipids_1
Indicates whether participant fasted for at least eight hours prior to blood draw to measure lipids phenotypes.
encoded
UMLS
0=Participant did not fast_or fasted for fewer than eight hours prior to measurement of lipids phenotypes.||1=Participant fasted for at least eight hours prior to measurement of lipids phenotypes.
total_cholesterol_1
Blood mass concentration of total cholesterol
decimal
mg/dL
UMLS
triglycerides_1
Blood mass concentration of triglycerides
decimal
mg/dL
UMLS
hdl_1
Blood mass concentration of high-density lipoprotein cholesterol
decimal
mg/dL
UMLS
ldl_1
Blood mass concentration of low-density lipoprotein cholesterol
decimal
mg/dL
UMLS
vte_prior_history_1
An indicator of whether a subject had a venous thromboembolism (VTE) event prior to the start of the medical review process (including self-reported events).
encoded
UMLS
0=did not have prior VTE event||1=had prior VTE event
vte_case_status_1
An indicator of whether a subject experienced a venous thromboembolism event (VTE) that was verified by adjudication or by medical professionals.
encoded
UMLS
0=Not known to ever have a VTE event_either self-reported or from medical records||1=Experienced a VTE event as verified by adjudication or by medical professionals
age_at_*
For each phenotypic value for a given subject, an associated age at measurement is provided.
decimal
years
See TOPMed Harmonization Strategies for more information.
unit_*
For each harmonized variable, a paired “unit_variable” is provided, whose value indicates where in the documentation to look to find the set of component variables and the algorithm used to harmonize those variables.
encoded
See TOPMed Harmonization Strategies for more information.